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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OASIS Antibody (C-term)   

OASIS Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OASIS Antibody (C-term) AP6229a
    The anti-OASIS C-term Antibody (Cat.#AP6229a) is used in Western blot to detect OASIS in A375 lysate.
  • IHC-P - OASIS Antibody (C-term) AP6229a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96BA8
Other Accession Q66HA2, Q9Z125, NP_443086
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57005 Da
Antigen Region 491-519 aa
Additional Information
Gene ID 90993
Other Names Cyclic AMP-responsive element-binding protein 3-like protein 1, cAMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced substance, OASIS, Processed cyclic AMP-responsive element-binding protein 3-like protein 1, CREB3L1, OASIS
Target/Specificity This OASIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-519 amino acids from the C-terminal region of human OASIS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOASIS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CREB3L1
Synonyms OASIS
Function Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Tissue Location Ubiquitously expressed with high levels in pancreas and prostate. Expressed at relatively lower levels in brain.
Research Areas
Citations (0)

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OASIS is a putative CREB/ATF family transcription factor with a putative C-terminal hydrophobic transmembrane domain. It can activate transcription through box-B elements but not through CRE of somatostatin. Shortening of the OASIS transmembrane domain results in a significant increase in transcriptional activity and changes its subcellular localization from the endoplasmic reticulum to the nucleus.


Omori, Y., et al., Biochem. Biophys. Res. Commun. 293(1):470-477 (2002).

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Cat# AP6229a
(40 western blots)
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