|Application ||WB, E|
|Other Accession||Q62785, Q3UHX2|
|Calculated MW||20630 Da|
|Antigen Region||142-171 aa|
|Other Names||28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PAP, PDGFA-associated protein 1, PAP1, PDAP1, HASPP28|
|Target/Specificity||This PDAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-171 amino acids from the C-terminal region of human PDAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Precautions||PDAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB.|
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Provided below are standard protocols that you may find useful for product applications.
Human PDAP1 encodes a deduced 181-amino acid protein expressed in all tissues test with the exception of liver, most abundantly in brain. PDAP1 enhances PDGFA-stimulated cell growth in mouse fibroblasts, but inhibits the mitogenic effect of PDGFB. The binding between PDGFA and PDAP1 is a low affinity/high capacity interaction, as determined by sold-phase studies.
Fischer, W.H., et al., J. Neurochem. 66(5):2213-2216 (1996).
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