|Application ||WB, E|
|Other Accession||Q62785, Q3UHX2|
|Calculated MW||20630 Da|
|Antigen Region||142-171 aa|
|Other Names||28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PAP, PDGFA-associated protein 1, PAP1, PDAP1, HASPP28|
|Target/Specificity||This PDAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-171 amino acids from the C-terminal region of human PDAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Human PDAP1 encodes a deduced 181-amino acid protein expressed in all tissues test with the exception of liver, most abundantly in brain. PDAP1 enhances PDGFA-stimulated cell growth in mouse fibroblasts, but inhibits the mitogenic effect of PDGFB. The binding between PDGFA and PDAP1 is a low affinity/high capacity interaction, as determined by sold-phase studies.
Fischer, W.H., et al., J. Neurochem. 66(5):2213-2216 (1996).
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