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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SCDGFB Antibody (Center)   

SCDGFB Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SCDGFB Antibody (Center) AP6263a
    Western blot analysis of lysate from mouse liver tissue lysate, using SCDGFB Antibody (Center)(Cat. #AP6263A). AP6263A was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.
  • WB - SCDGFB Antibody (Center) AP6263a
    Western blot analysis of lysate from rat kidney tissue lysate, using SCDGFB Antibody (Center)(Cat. #AP6263A). AP6263A was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
  • IHC-P - SCDGFB Antibody (Center) AP6263a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • IHC-P - SCDGFB Antibody (Center) AP6263a
    SCDGFB Antibody (Center) (Cat. #AP6263a)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCDGFB Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9EQT1
Other Accession Q6V9H4, Q925I7
Reactivity Human
Predicted Mouse, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42809 Da
Antigen Region 313-341 aa
Additional Information
Gene ID 66018
Other Names Platelet-derived growth factor D, PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, Platelet-derived growth factor D, latent form, PDGFD latent form, Platelet-derived growth factor D, receptor-binding form, PDGFD receptor-binding form, Pdgfd, Iegf, Scdgfb
Target/Specificity This SCDGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-341 amino acids from the Central region of rat SCDGFB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCDGFB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Pdgfd
Synonyms Iegf, Scdgfb
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
Cellular Location Secreted. Note=Released by platelets upon wounding.
Tissue Location Widely expressed. Expressed at high levels in the kidney, adrenal glands, eye and CNS. In the kidney the localization is confined to arterial and arteriolar vascular smooth muscle cells and is also detected at low levels in the glomeruli In the eye in the anterior segment it is localized to the iris and ciliary body. In the retina localizes intensely to the outer plexiform layer, which contains photoreceptor axons and the synaptic layer between photoreceptors and second order neurons. In the spinal cord, prominently expressed in the motorneurons.
Research Areas
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$ 295.00
$ 99.00
Cat# AP6263a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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