TOB2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q14106 |
Other Accession | Q61471, P50616 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36632 Da |
Antigen Region | 17-46 aa |
Gene ID | 10766 |
---|---|
Other Names | Protein Tob2, Protein Tob4, Transducer of erbB-2 2, TOB2, KIAA1663, TOB4, TROB2 |
Target/Specificity | This TOB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human TOB2. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TOB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TOB2 |
---|---|
Synonyms | KIAA1663, TOB4, TROB2 |
Function | Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
TOB2 belongs to the TOB /BTG1 family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.
References
Sasajima,H., Eur. J. Biochem. 269 (14), 3596-3604 (2002)
Yoshida,Y., Jpn. J. Cancer Res. 92 (6), 592-596 (2001)
Suzuki,T., Genes Cells 6 (2), 131-138 (2001)
Ikematsu,N., Oncogene 18 (52), 7432-7441 (1999)
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