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GRB2 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6283b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
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GRB2 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P62993 |
| Other Accession | P62994, Q60631 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 25206 Da |
GRB2 Antibody (N-term) - Additional info | |
| Gene ID 2885 | |
| Other Names GRB2; ASH; Growth factor receptor-bound protein 2; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2 | |
| Target/Specificity This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57~87 amino acids from the N-terminal region of human GRB2. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions GRB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
GRB2 Antibody (N-term) - Protein Information | |
| Name GRB2 | |
| Synonyms ASH | |
| Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | |
| Cellular Location Nucleus. Cytoplasm. Endosome. Golgi apparatus (By similarity) | |
GRB2 Antibody (N-term) - Related products
AP6283b: GRB2 Antibody (N-term)
AP6283c: GRB2 Antibody (Center)
DC00301: Human GRB2 cDNA Clone
LY11018a: GRB2 Over-expression Lysate
BP6283a: GRB2 Antibody (Y209) Blocking Peptide
BP6283b: GRB2 Antibody (N-term) Blocking Peptide
BP6283c: GRB2 Antibody (Center) Blocking Peptide
AJ1331a: GRB2 Antibody (C-term)
GRB2 Antibody (N-term) - Application data
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Western blot analysis of anti-GRB2 Antibody (N-term) (Cat.#AP6283b) in HepG2 cell line lysates (35ug/lane). GRB2(arrow) was detected using the purified Pab.
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Western blot analysis of anti-GRB2 Antibody (N-term) (Cat.#AP6283b) in mouse spleen tissue lysates (35ug/lane).GRB2(arrow) was detected using the purified Pab.
GRB2 Antibody (N-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences.
REFERENCES
Kondo,A., J. Biol. Chem. 283 (3), 1428-1436 (2008) Morimatsu,M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007) Martinez,N., Cell. Signal. 19 (11), 2277-2285 (2007)
