|Application ||WB, IHC-P, E|
|Other Accession||P23565, P46660, Q08DH7|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||55391 Da|
|Antigen Region||290-319 aa|
|Other Names||Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, NF-66, Neurofilament-66, Neurofilament 5, INA, NEF5|
|Target/Specificity||This INA (alpha internexin) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the Central region of human INA (alpha internexin).|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||INA (alpha internexin) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.|
|Tissue Location||Found predominantly in adult CNS.|
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Provided below are standard protocols that you may find useful for product applications.
INA is a class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Armstrong,R.A.,Eur. J. Neurol. 13 (5), 528-532 (2006)
Suzuki,T., Eur. J. Neurosci. 21 (2), 339-350 (2005)
Cairns,N.J., Am. J. Pathol. 164 (6), 2153-2161 (2004)
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