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INA (alpha internexin) Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - INA (alpha internexin) Antibody (Center) AP6284c
    Western blot analysis of INA (arrow) using rabbit polyclonal INA Antibody (Center) (Cat.#AP6284c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the INA gene (Lane 2) (Origene Technologies).
  • IHC-P - INA (alpha internexin) Antibody (Center) AP6284c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with INA antibody (Center) (Cat.#AP6284c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q16352
Other Accession P23565, P46660, Q08DH7
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55391 Da
Antigen Region 290-319 aa
Additional Information
Gene ID 9118
Other Names Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, NF-66, Neurofilament-66, Neurofilament 5, INA, NEF5
Target/Specificity This INA (alpha internexin) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the Central region of human INA (alpha internexin).
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsINA (alpha internexin) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INA
Synonyms NEF5
Function Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Tissue Location Found predominantly in adult CNS.
Research Areas
Citations (0)

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Background

INA is a class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

References

Armstrong,R.A.,Eur. J. Neurol. 13 (5), 528-532 (2006)
Suzuki,T., Eur. J. Neurosci. 21 (2), 339-350 (2005)
Cairns,N.J., Am. J. Pathol. 164 (6), 2153-2161 (2004)

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$ 295.00
$ 99.00
Cat# AP6284c
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Quantity:
(40 western blots)
Availability: In Stock
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