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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MEF2C Antibody (S396)   

MEF2C Antibody (S396)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MEF2C Antibody (S396) AP6285b
    All lanes : Anti-MEF2C Antibody (S396) at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - MEF2C Antibody (S396) AP6285b
    Western blot analysis of MEF2C (arrow) using rabbit polyclonal MEF2C Antibody (S396) (RB11048). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MEF2C gene (Lane 2) (Origene Technologies).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q06413
Other Accession A4UTP7
Reactivity Human
Predicted Pig
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51221 Da
Antigen Region 374-403 aa
Additional Information
Gene ID 4208
Other Names Myocyte-specific enhancer factor 2C, MEF2C
Target/Specificity This MEF2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from human MEF2C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMEF2C Antibody (S396) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEF2C
Function Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Cellular Location Nucleus.
Tissue Location Expressed in brain and skeletal muscle.
Research Areas
Citations (0)

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MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.


Konig, S., et al., J. Biol. Chem. 279(27):28187-28196 (2004).
Maeda, T., et al., J. Biol. Chem. 277(50):48889-48898 (2002).
Maeda, T., et al., Biochem. Biophys. Res. Commun. 294(4):791-797 (2002).
Janson, C.G., et al., Brain Res. Mol. Brain Res. 97(1):70-82 (2001).
Krainc, D., et al., Genomics 29(3):809-811 (1995).

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$ 295.00
$ 99.00
Cat# AP6285b
(40 western blots)
Availability: In Stock
Bulk Size
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