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ABAD Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6307b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ABAD Antibody (C-term) - Product info | |
| Application | WB, IHC
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| Primary Accession | Q6IBS9 |
| Other Accession | O70351, O08756, Q99714, O02691 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
ABAD Antibody (C-term) - Additional info | |
| Other Names hydroxyacyl-Coenzyme A dehydrogenase, type II isoform 1; 3-hydroxyacyl-CoA dehydrogenase type II; Type II HADH; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide binding protein; Short-chain type dehydrogenase/reductase XH98G2 ; ERAB, HSD17B10, SCHAD; HADH2 protein | |
| Target/Specificity This ABAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ABAD. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABAD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABAD Antibody (C-term) - Protein Information | |
ABAD Antibody (C-term) - Related products
AP6307a: ABAD Antibody (Center)
AP6307b: ABAD Antibody (C-term)
AP6307c: HADH2 Antibody (C-term P222)
AP6307d: HADH2 Antibody (Center)
RI12577: HSD17B10 predesign siRNA
DC02465: Human HSD17B10 cDNA Clone
LY10129a: HADH2 Over-expression Lysate
LY13769a: HSD17B10 Over-expression Lysate
BP6307a: ABAD Antibody (Center) Blocking Peptide
BP6307b: ABAD Antibody (C-term) Blocking Peptide
BP6307c: HADH2 Antibody (C-term P222) Blocking Peptide
ABAD Antibody (C-term) - Application data
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Western blot analysis of anti-ABAD Pab (Cat. #AP6307b) in mouse kidney tissue lysate.ABAD(arrow) was detected using the purified Pab.
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Immunohistochemistry on Formalin-fixed and paraffin-embedded human prostate tissue. (Top)Coloration with the Anti-ABAD antibody at a 1:20 concentration. (Bottom)Antibody adsorbed to the antigen (peptide), negative control.Disappearance of cytoplasmic staining indicating the antibody is specific. Data and protocol courtesy of Marie-Hélène Levesque, Centre de Recherche du CHUL, Canada.
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ABAD Antibody (C214) (Cat. #AP6307b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ABAD antibody detected the ABAD protein (arrow).
ABAD Antibody (C-term) - Research Areas
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BACKGROUND
Amyloid b-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases; unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ABAD appears to trigger cell stress induced by the amyloid peptide.
REFERENCES
FASEB J. 19 (6), 597-598 (2005) J. Mol. Biol. 342 (3), 943-952 (2004) Science 304 (5669), 448-452 (2004) FEBS Lett. 451 (3), 238-242 (1999) J. Biol. Chem. 274 (21), 15014-15019 (1999)
