Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   RCAN1/DSCR1 Antibody (C-term)   

RCAN1/DSCR1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RCAN1/DSCR1 Antibody (C-term) AP6315c
    Endothelial cell lysate transferred to membrane was incubated with primary antibody at a 1:500 dilution in 2% BSA in TBST at 4deg C overnight. Data courtesy of Dr. Katherine Healey, NWCRF Institute, School of Biological Sciences, University of Wales Bangor.
  • WB - RCAN1/DSCR1 Antibody (C-term) AP6315c
    The anti-RCAN1/DSCR1 Pab (Cat. #AP6315c) is used in Western blot to detect RCAN1/DSCR1 in endothelial tissue lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53805
Other Accession Q6IN33, Q9JHG6, O35847, Q3ZBP4, Q7Z555, Q6XXM7
Reactivity Human
Predicted Mouse, Rat, Hamster, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28079 Da
Antigen Region 222-252 aa
Additional Information
Gene ID 1827
Other Names Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1, RCAN1, ADAPT78, CSP1, DSC1, DSCR1
Target/Specificity This RCAN1/DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human DSCR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRCAN1/DSCR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RCAN1
Synonyms ADAPT78, CSP1, DSC1, DSCR1
Function Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Tissue Location Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues
Research Areas
Citations ( 0 )


DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.


Minami, T., et al., J. Biol. Chem. 279(48):50537-50554 (2004). Yao, Y.G., et al., Biochem. Biophys. Res. Commun. 321(3):648-656 (2004). Michtalik, H.J., et al., Free Radic. Biol. Med. 37(4):454-462 (2004). Hesser, B.A., et al., Blood 104(1):149-158 (2004). Iizuka, M., et al., Biochem. Biophys. Res. Commun. 41(4):334-344 (2004).

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 295.00
$ 99.00
Cat# AP6315c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions