|Application ||WB, IHC-P, IF, E|
|Calculated MW||26788 Da|
|Antigen Region||171-197 aa|
|Other Names||Hepatoma-derived growth factor, HDGF, High mobility group protein 1-like 2, HMG-1L2, HDGF, HMG1L2|
|Target/Specificity||This HDGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-197 amino acids from the C-terminal region of human HDGF.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Precautions||HDGF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.|
|Cellular Location||Cytoplasm. Nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
HDGF is a member of the hepatoma-derived growth factor family. This protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation.
Thakar,K., FEBS J. 275 (7), 1411-1426 (2008)
Chang,K.C.,Int. J. Cancer 121 (5), 1059-1065 (2007)
Yamamoto,S., Ann. Surg. Oncol. 14 (7), 2141-2149 (2007)
Uyama,H., Clin. Cancer Res. 12 (20 PT 1), 6043-6048 (2006)
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