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HDGF Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, WB, IHC-P, E |
|---|---|
| Primary Accession | P51858 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26788 Da |
| Antigen Region | 171-197 aa |
| Gene ID | 3068 |
|---|---|
| Other Names | Hepatoma-derived growth factor, HDGF, High mobility group protein 1-like 2, HMG-1L2, HDGF, HMG1L2 |
| Target/Specificity | This HDGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-197 amino acids from the C-terminal region of human HDGF. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HDGF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HDGF |
|---|---|
| Synonyms | HMG1L2 |
| Function | [Isoform 1]: Acts as a transcriptional repressor (PubMed:17974029). Has mitogenic activity for fibroblasts (PubMed:11751870, PubMed:26845719). Heparin-binding protein (PubMed:15491618). |
| Cellular Location | [Isoform 1]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Note=Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477) [Isoform 3]: Nucleus. Cytoplasm Secreted, extracellular exosome Note=Secreted by exosomes and is located on the outer exosome surface |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
HDGF is a member of the hepatoma-derived growth factor family. This protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation.
References
Thakar,K., FEBS J. 275 (7), 1411-1426 (2008)
Chang,K.C.,Int. J. Cancer 121 (5), 1059-1065 (2007)
Yamamoto,S., Ann. Surg. Oncol. 14 (7), 2141-2149 (2007)
Uyama,H., Clin. Cancer Res. 12 (20 PT 1), 6043-6048 (2006)
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