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ARPC1A Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP6519b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP6519b-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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ARPC1A Antibody (C-term) - Product info | |
| Application | WB, IHC, IF, FC
|
| Primary Accession | Q92747 |
| Other Accession | Q99PD4, Q9R0Q6, Q1JP79 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 41569 Da |
ARPC1A Antibody (C-term) - Additional info | |
| Gene ID 10552 | |
| Other Names ARPC1A; SOP2L; Actin-related protein 2/3 complex subunit 1A; SOP2-like protein | |
| Target/Specificity This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293~323 amino acids from the C-terminal region of human ARPC1A. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 IF~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ARPC1A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ARPC1A Antibody (C-term) - Protein Information | |
| Name ARPC1A | |
| Synonyms SOP2L | |
| Function Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks | |
| Cellular Location Cytoplasm, cytoskeleton (Probable). | |
ARPC1A Antibody (C-term) - Related products
AP6519b: ARPC1A Antibody (C-term)
AP6519c: ARPC1A Antibody (Center)
RI10411: ARPC1A predesign siRNA
DC07286: Human ARPC1A cDNA Clone
LY11814a: ARPC1A Over-expression Lysate
ARPC1A Antibody (C-term) - Application data
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Western blot analysis of ARPC1A Antibody (C-term) (Cat. #AP6519b) in Hela cell line lysates (35ug/lane). ARPC1A (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ARPC1A Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Immunofluorescence analysis of ARPC1A Antibody (C-term) with hela cells. 0.025 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.Red counterstaining is PI.
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Flow cytometric analysis of WiDr cells using ARPC1A Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ARPC1A Antibody (C-term) - Research Areas
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BACKGROUND
ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.
REFERENCES
Laurila,E., Genes Chromosomes Cancer 48 (4), 330-339 (2009) Machesky,L.M., Biochem. J. 328 (PT 1), 105-112 (1997)