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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   ENDOG Antibody (C-term)   

ENDOG Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ENDOG Antibody (C-term) AP6571B
    Western blot analysis of ENDOG Antibody (C-term) (Cat. 3AP6571b) in 293,K562,Jurkat,NCI-H460 cell line lysates and mouse kidney tissues lysates(35ug/lane). ENDOG (arrow) was detected using the purified Pab.
  • FC - ENDOG Antibody (C-term) AP6571B
    ENDOG Antibody (C-term) (Cat. #AP6571b) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14249
Other Accession O08600, P38447
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32620 Da
Antigen Region 188-217 aa
Additional Information
Gene ID 2021
Other Names Endonuclease G, mitochondrial, Endo G, 3130-, ENDOG
Target/Specificity This ENDOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the C-terminal region of human ENDOG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsENDOG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).
Cellular Location Mitochondrion.
Research Areas
Citations (0)

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ENDOG is a nuclear encoded endonuclease that is localized in the mitochondrion. The protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.


Noda,T., Apoptosis 14 (3), 287-297 (2009)
Wu,S.L., J. Biomed. Sci. 16, 6 (2009)
Ahn,C.H., APMIS 116 (6), 534-537 (2008)

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$ 295.00
$ 99.00
Cat# AP6571B
(40 western blots)
Availability: In Stock
Bulk Size
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