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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GNS Antibody (Center S298)   

GNS Antibody (Center S298)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GNS Antibody (Center S298) AP6574b
    Western blot analysis of GNS Antibody (Center S298) (Cat. #AP6574b) in NCI-H460, Hela, 293 cell line lysates (35ug/lane). GNS (arrow) was detected using the purified Pab.
  • IHC-P - GNS Antibody (Center S298) AP6574b
    GNS Antibody (Center S298) (Cat. #AP6574b) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GNS Antibody (Center S298) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GNS Antibody (Center S298) AP6574b
    GNS Antibody (Center S298) (Cat. #AP6574b) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15586
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62082 Da
Antigen Region 283-313 aa
Additional Information
Gene ID 2799
Other Names N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS
Target/Specificity This GNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the Central region of human GNS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGNS Antibody (Center S298) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNS
Cellular Location Lysosome.
Research Areas
Citations (0)

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GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.


Zhang,H., Li,X.J., Nat. Biotechnol. 21 (6), 660-666 (2003)

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$ 295.00
$ 99.00
Cat# AP6574b
(40 western blots)
Availability: In Stock
Bulk Size
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