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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   SPB3 Antibody (N-term)   

SPB3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPB3 Antibody (N-term) AP6579a
    Western blot analysis of SPB3 antibody (N-term) (Cat. #AP6579a) in 293 cell line lysates (35ug/lane). SPB3 (arrow) was detected using the purified Pab.
  • IHC-P - SPB3 Antibody (N-term) AP6579a
    SPB3 Antibody (N-term) (Cat. #AP6579a) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SPB3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SPB3 Antibody (N-term) AP6579a
    SPB3 Antibody (N-term) (Cat. #AP6579a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P29508
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44565 Da
Antigen Region 40-69 aa
Additional Information
Gene ID 6317
Other Names Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA, SCCA1
Target/Specificity This SPB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SPB3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPB3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SCCA, SCCA1
Function May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Cellular Location Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level
Tissue Location Squamous cells. Expressed in some hepatocellular carcinoma (at protein level)
Research Areas
Citations (0)

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SPB3 may act as a protease inhibitor to modulate the host immune response against tumor cells.


Turato,C., Dig Liver Dis 41 (3), 212-216 (2009)
Ahmed,S.T., Biochem. Biophys. Res. Commun. 378 (4), 821-825 (2009)

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$ 295.00
$ 99.00
Cat# AP6579a
(40 western blots)
Availability: In Stock
Bulk Size
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