|Application ||WB, IHC-P, FC, E|
|Calculated MW||36414 Da|
|Antigen Region||7-34 aa|
|Other Names||Calponin-3, Calponin, acidic isoform, CNN3|
|Target/Specificity||This Calponin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human Calponin-3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Calponin-3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.|
|Tissue Location||Expressed in both non-smooth muscle tissues as well as smooth muscle tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Calponin-3 is a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. This protein is associated with the cytoskeleton but is not involved in contraction.
Vinatzer,U., Clin. Cancer Res. 14 (20), 6426-6431 (2008)
Haag,J., Exp. Cell Res. 313 (16), 3386-3394 (2007)
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