- CITATIONS: 1
|Application ||WB, IHC-P, FC, E|
|Other Accession||Q9XSD9, P21793, Q9TTE2|
|Calculated MW||39747 Da|
|Antigen Region||122-150 aa|
|Other Names||Decorin, Bone proteoglycan II, PG-S2, PG40, DCN, SLRR1B|
|Target/Specificity||This DCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the Central region of human DCN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DCN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May affect the rate of fibrils formation.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
Provided below are standard protocols that you may find useful for product applications.
DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines.
Goldoni,S., J. Cell Biol. 185 (4), 743-754 (2009)
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