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ACADVL Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6597a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ACADVL Antibody (N-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P49748 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 70390 Da |
ACADVL Antibody (N-term) - Additional info | |
| Gene ID 37 | |
| Other Names ACADVL; VLCAD; Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | |
| Target/Specificity This ACADVL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50~79 amino acids from the N-terminal region of human ACADVL. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACADVL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACADVL Antibody (N-term) - Protein Information | |
| Name ACADVL | |
| Synonyms VLCAD | |
| Function Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons | |
| Cellular Location Mitochondrion inner membrane. | |
ACADVL Antibody (N-term) - Related products
AP6597a: ACADVL Antibody (N-term)
RI10044: ACADVL predesign siRNA
ACADVL Antibody (N-term) - Application data
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Western blot analysis of ACADVL antibody (N-term) (Cat. #AP6597a) in NCI-H460 cell line lysates (35ug/lane). ACADVL (arrow) was detected using the purified Pab.
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(LEFT)Formalin-fixed and paraffin-embedded human lung carcinoma with ACADVL Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. (RIGHT)Flow cytometric analysis of NCI-H292 cells using ACADVL Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ACADVL Antibody (N-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in its gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.
REFERENCES
Gobin-Limballe,S., Am. J. Hum. Genet. 81 (6), 1133-1143 (2007) Zia,A., J. Inherit. Metab. Dis. 30 (5), 817 (2007)
