|Application ||WB, IHC-P, E|
|Calculated MW||20547 Da|
|Antigen Region||131-158 aa|
|Other Names||Actin-related protein 2/3 complex subunit 3, Arp2/3 complex 21 kDa subunit, p21-ARC, ARPC3, ARC21|
|Target/Specificity||This ARPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the C-terminal region of human ARPC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARPC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection.|
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Provided below are standard protocols that you may find useful for product applications.
ARPC3 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein, the p21 subunit, has yet to be determined.
Dubois,T., Nat. Cell Biol. 7 (4), 353-364 (2005)
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