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BAALC Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q8WXS3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 15551 Da |
| Antigen Region | 41-68 aa |
| Gene ID | 79870 |
|---|---|
| Other Names | Brain and acute leukemia cytoplasmic protein, BAALC |
| Target/Specificity | This BAALC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human BAALC. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BAALC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BAALC {ECO:0000303|PubMed:11707601} |
|---|---|
| Function | May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. |
| Cellular Location | Cytoplasm. Synapse, synaptosome {ECO:0000250|UniProtKB:Q920K5}. Membrane raft {ECO:0000250|UniProtKB:Q920K5}. Postsynaptic density {ECO:0000250|UniProtKB:Q920K5}. Note=In neurons, localizes to postsynaptic lipid rafts (By similarity). In myocardial and skeletal muscle cells, localizes to the cytoplasm adjacent to the inner cell membrane, polarized to one end of the myocyte (By similarity) {ECO:0000250|UniProtKB:Q8VHV1, ECO:0000250|UniProtKB:Q920K5} |
| Tissue Location | Predominantly expressed in neuroectoderm-derived tissues. Expressed in the brain and spinal cord, and at low levels, in the adrenal gland. In the bone marrow, confined to the CD34+ progenitor cells. Not found in peripheral blood mononuclear cells, nor lymph nodes. Tends to be expressed at high levels in acute myeloid leukemia and glioblastoma cells. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
BAALC may play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
References
Kuila,N., Leuk. Res. 33 (4), 594-596 (2009)
Satoskar,A.A., Gene Expr. Patterns 5 (4), 463-473 (2005)
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$ 365.00
$ 140.00
Cat# AP6605a
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