|Application ||WB, IHC-P, FC, E|
|Calculated MW||19224 Da|
|Antigen Region||41-68 aa|
|Other Names||Brain and acute leukemia cytoplasmic protein, BAALC|
|Target/Specificity||This BAALC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human BAALC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BAALC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.|
|Cellular Location||Cytoplasm. Membrane. Note=Postsynaptic lipid rafts.|
|Tissue Location||Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm- derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin|
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Provided below are standard protocols that you may find useful for product applications.
BAALC may play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
Kuila,N., Leuk. Res. 33 (4), 594-596 (2009)
Satoskar,A.A., Gene Expr. Patterns 5 (4), 463-473 (2005)
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