|Application ||FC, WB, IHC-P, E|
|Calculated MW||48125 Da|
|Antigen Region||379-408 aa|
|Other Names||Clusterin-associated protein 1, Qilin, CLUAP1, KIAA0643|
|Target/Specificity||This CLUAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-408 amino acids from the C-terminal region of human CLUAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLUAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity).|
|Cellular Location||Nucleus. Cell projection, cilium.|
|Tissue Location||Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland. Highly expressed in colon cancer and osteosarcoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
CLUAP1 may play a role in cell proliferation or apoptosis.
Ishikura,H., Int. J. Oncol. 30 (2), 461-467 (2007)
Takahashi,M., Oncogene 23 (57), 9289-9294 (2004)
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