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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   DOM3Z Antibody (N-term Y88)   

DOM3Z Antibody (N-term Y88)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DOM3Z Antibody (N-term Y88) AP6635a
    Western blot analysis of DOM3Z antibody (N-term Y88) (Cat. #AP6635a) in MCF-7 cell line lysates (35ug/lane). DOM3Z (arrow) was detected using the purified Pab.
  • FC - DOM3Z Antibody (N-term Y88) AP6635a
    Flow cytometric analysis of MDA-231 cells using DOM3Z Antibody (N-term Y88)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - DOM3Z Antibody (N-term Y88) AP6635a
    Western blot analysis of DOM3Z (arrow) using rabbit polyclonal DOM3Z Antibody (N-term Y88) (Cat. #AP6635a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DOM3Z gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O77932
Other Accession Q6MG77, O70348, Q5E9Y5
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 44929 Da
Antigen Region 73-99 aa
Additional Information
Gene ID 1797
Other Names Decapping and exoribonuclease protein, DXO, 3113-, 361-, Dom-3 homolog Z, DXO, DOM3L, DOM3Z, NG6
Target/Specificity This DOM3Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-99 amino acids from the N-terminal region of human DOM3Z.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDOM3Z Antibody (N-term Y88) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DXO
Synonyms DOM3L, DOM3Z, NG6
Function Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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The function of DOM3Z is unknown, but its ubiquitous expression and conservation in both simple and complex eukaryotes suggests that its gene may be a housekeeping gene.


Lehner,B., Genome Res. 14 (7), 1315-1323 (2004)

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$ 295.00
$ 99.00
Cat# AP6635a
(40 western blots)
Availability: In Stock
Bulk Size
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