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FTCD Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP6646b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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FTCD Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | O95954 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 58927 Da |
FTCD Antibody (C-term) - Additional info | |
| Gene ID 10841 | |
| Other Names FTCD; Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; LCHC1; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; Formimidoyltetrahydrofolate cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase | |
| Target/Specificity This FTCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416~445 amino acids from the C-terminal region of human FTCD. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions FTCD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
FTCD Antibody (C-term) - Protein Information | |
| Name FTCD | |
| Function Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | |
| Cellular Location Cytoplasm, cytoskeleton, centrosome, centriole. Golgi apparatus (By similarity). Note=More abundantly located around the mother centriole | |
FTCD Antibody (C-term) - Related products
AP6646b: FTCD Antibody (C-term)
AP6646c: FTCD Antibody (Center)
BP6646b: FTCD Antibody (C-term) Blocking Peptide
BP6646c: FTCD Antibody (Center) Blocking Peptide
AT2112a: FTCD Antibody (monoclonal) (M01)
AT2113a: FTCD Antibody (monoclonal) (M02)
FTCD Antibody (C-term) - Application data
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Western blot analysis of FTCD antibody (C-term) (Cat. #AP6646b) in mouse liver tissue lysates (35ug/lane). FTCD (arrow) was detected using the purified Pab.
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FTCD Antibody (C-term) (RB18716) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FTCD Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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FTCD Antibody (C-term) (Cat. #AP6646b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
FTCD Antibody (C-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.
REFERENCES
Hilton,J.F., Hum. Mutat. 22 (1), 67-73 (2003)