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FTCD Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)

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United States
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Ordering Information
Catalog # Size Availability Price  
AP6646b 0.1 mg 400 ul In Stock $ 255.00 Add to cart
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FTCD Antibody (C-term) - Product info

ApplicationWB, IHC, FC
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionO95954
ReactivityHuman, Mouse
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW58927 Da

FTCD Antibody (C-term) - Additional info

Gene ID 10841
Other Names
FTCD; Formimidoyltransferase-cyclodeaminase; Formiminotransferase-cyclodeaminase; LCHC1; Glutamate formimidoyltransferase; Glutamate formiminotransferase; Glutamate formyltransferase; Formimidoyltetrahydrofolate cyclodeaminase; Formiminotetrahydrofolate cyclodeaminase
Target/Specificity
This FTCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416~445 amino acids from the C-terminal region of human FTCD.
Dilution
WB~~1:50~100
IHC~~1:50~100
FC~~1:10~50
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
FTCD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.

FTCD Antibody (C-term) - Protein Information

Name FTCD
Function
Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool
Cellular Location
Cytoplasm, cytoskeleton, centrosome, centriole. Golgi apparatus (By similarity). Note=More abundantly located around the mother centriole

FTCD Antibody (C-term) - Related products

AP6646b: FTCD Antibody (C-term)

AP6646c: FTCD Antibody (Center)

RI12079: FTCD predesign siRNA

BP6646b: FTCD Antibody (C-term) Blocking Peptide

BP6646c: FTCD Antibody (Center) Blocking Peptide

AT2112a: FTCD Antibody (monoclonal) (M01)

AT2113a: FTCD Antibody (monoclonal) (M02)

AF1003a: 58K Golgi protein(N-Term)/FTCD Antibody

AF1003b: 58KGolgi protein(Internal)/FTCD Antibody

FTCD Antibody (C-term) - Application data

  • Western blot analysis of FTCD antibody (C-term) (Cat. #AP6646b) in mouse liver tissue lysates (35ug/lane). FTCD (arrow) was detected using the purified Pab.

  • FTCD Antibody (C-term) (RB18716) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FTCD Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

  • FTCD Antibody (C-term) (Cat. #AP6646b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

FTCD Antibody (C-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

FTCD is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool.

REFERENCES

Hilton,J.F., Hum. Mutat. 22 (1), 67-73 (2003)