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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NKRF Antibody (Center)   

NKRF Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NKRF Antibody (Center) AP6660c
    Western blot analysis of NKRF antibody (Center) (Cat. #AP6660c) in Jurkat cell line lysates (35ug/lane). NKRF (arrow) was detected using the purified Pab.
  • IHC-P - NKRF Antibody (Center) AP6660c
    Formalin-fixed and paraffin-embedded human brain reacted with NKRF Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15226
Other Accession Q8BY02
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 77673 Da
Antigen Region 205-233 aa
Additional Information
Gene ID 55922
Other Names NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, Transcription factor NRF, NKRF, ITBA4, NRF
Target/Specificity This NKRF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human NKRF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNKRF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ITBA4, NRF
Function Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Cellular Location Nucleus, nucleolus
Tissue Location Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney
Research Areas
Citations (0)

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NKRF is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.


Ho,S.C., J. Immunol. 183 (1), 411-420 (2009)
Glanz,A., Immunol. Cell Biol. 86 (7), 622-630 (2008)

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$ 295.00
$ 99.00
Cat# AP6660c
(40 western blots)
Availability: In Stock
Bulk Size
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