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SERPING1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SERPING1 Antibody (Center) AP6673b
    Western blot analysis of SERPING1 antibody (Center) (Cat. #AP6673b) in Jurkat cell line lysates (35ug/lane). SERPING1 (arrow) was detected using the purified Pab.
  • IHC-P - SERPING1 Antibody (Center) AP6673b
    SERPING1 Antibody (Center) (Cat. #AP6673b) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPING1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - SERPING1 Antibody (Center) AP6673b
    Confocal immunofluorescent analysis of SERPING1 Antibody (Center)(Cat#AP6673b) with NCI-H292 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05155
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55154 Da
Antigen Region 285-314 aa
Additional Information
Gene ID 710
Other Names Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, SERPING1, C1IN, C1NH
Target/Specificity This SERPING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SERPING1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPING1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C1IN, C1NH
Function Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Cellular Location Secreted.
Research Areas
Citations (0)

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SERPING1 is a highly glycosylated plasma protein involved in the regulation of the complement cascade. This protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE).


Park,K.H., Mol. Vis. 15, 200-207 (2009)
Gosswein,T., Cytogenet. Genome Res. 121 (3-4), 181-188 (2008)

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Cat# AP6673b
(40 western blots)
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