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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AOX1 Antibody (Center)   

AOX1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AOX1 Antibody (Center) AP6700c
    Anti-AOX1 Antibody (Center) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 148 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • FC - AOX1 Antibody (Center) AP6700c
    AOX1 Antibody (Center) (Cat.#AP6700c) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q06278
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 147918 Da
Antigen Region 698-726 aa
Additional Information
Gene ID 316
Other Names Aldehyde oxidase, Aldehyde oxidase 1, Azaheterocycle hydroxylase, 1173-, AOX1, AO
Target/Specificity This AOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 698-726 amino acids from the Central region of human AOX1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAOX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AOX1
Synonyms AO
Function Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N- methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
Cellular Location Cytoplasm
Tissue Location Abundant in liver, expressed in adipose tissue and at lower levels in lung, skeletal muscle, pancreas. In contrast to mice, no significant gender difference in AOX1 expression level (at protein level).
Research Areas
Citations (0)

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AOX1 catalyzes: An aldehyde + H2O + O2 = a carboxylic acid + H2O2.


Wright,R.M., Proc. Natl. Acad. Sci. U.S.A. 90 (22), 10690-10694 (1993)

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$ 295.00
$ 99.00
Cat# AP6700c
(40 western blots)
Availability: In Stock
Bulk Size
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