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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   DCD Antibody (C-term)   

DCD Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DCD Antibody (C-term) AP6718b
    Western blot analysis of DCD antibody (C-term) (Cat. #AP6718b) in T47D cell line lysates (35ug/lane). DCD (arrow) was detected using the purified Pab.
  • IHC-P - DCD Antibody (C-term) AP6718b
    DCD Antibody (C-term) (RB18706) IHC analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCD Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - DCD Antibody (C-term) AP6718b
    DCD Antibody (C-term) (Cat. #AP6718b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P81605
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 11284 Da
Antigen Region 74-103 aa
Additional Information
Gene ID 117159
Other Names Dermcidin, 34--, Preproteolysin, Survival-promoting peptide, DCD-1, DCD, AIDD, DSEP
Target/Specificity This DCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human DCD.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCD
Synonyms AIDD, DSEP
Function DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.
Cellular Location Secreted.
Tissue Location Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml
Research Areas
Citations ( 0 )


DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.


Todorov,P.T., J. Biol. Chem. 272 (19), 12279-12288 (1997)

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$ 295.00
$ 99.00
Cat# AP6718b
(40 western blots)
Availability: In Stock
Bulk Size
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