|Application ||WB, E|
|Other Accession||Q9JHW1, O89001|
|Calculated MW||152931 Da|
|Antigen Region||1019-1048 aa|
|Other Names||Carboxypeptidase D, Metallocarboxypeptidase D, gp180, CPD|
|Target/Specificity||This CPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1019-1048 amino acids from the C-terminal region of human CPD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CPD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein.
Hoff,N.P., J. Clin. Immunol. 27 (6), 568-579 (2007)
O'Malley,P.G., Biochem. J. 390 (PT 3), 665-673 (2005)
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