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FBP2 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O00757 |
| Other Accession | Q9N0J6, Q2KJJ9 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36743 Da |
| Antigen Region | 250-281 aa |
| Gene ID | 8789 |
|---|---|
| Other Names | Fructose-1, 6-bisphosphatase isozyme 2, FBPase 2, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 2, Muscle FBPase, FBP2 |
| Target/Specificity | This FBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-281 amino acids from the C-terminal region of human FBP2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FBP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FBP2 |
|---|---|
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
| Cellular Location | Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration. |
| Tissue Location | Expressed in skeletal muscle (at protein level). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
FBP2 is a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate.
References
Gizak,A., Proteins 72 (1), 209-216 (2008)
Rakus,D., FEBS Lett. 579 (25), 5577-5581 (2005)
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$ 182.50
$ 70.00
Cat# AP6729b
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