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FBP2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FBP2 Antibody (C-term) AP6729b
    Western blot analysis of FBP2 Antibody (C-term) (Cat. #AP6729b) in mouse heart tissue lysates (35ug/lane). FBP2 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00757
Other Accession Q9N0J6, Q2KJJ9
Reactivity Human, Mouse
Predicted Bovine, Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36743 Da
Antigen Region 250-281 aa
Additional Information
Gene ID 8789
Other Names Fructose-1, 6-bisphosphatase isozyme 2, FBPase 2, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 2, Muscle FBPase, FBP2
Target/Specificity This FBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-281 amino acids from the C-terminal region of human FBP2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBP2
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Cellular Location Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. Note=In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
Tissue Location Expressed in skeletal muscle (at protein level).
Research Areas
Citations (0)

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FBP2 is a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate.


Gizak,A., Proteins 72 (1), 209-216 (2008)
Rakus,D., FEBS Lett. 579 (25), 5577-5581 (2005)

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Cat# AP6729b
(40 western blots)
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