|Application ||WB, IHC-P, FC, E|
|Other Accession||P45878, Q32PA9|
|Calculated MW||15649 Da|
|Antigen Region||11-41 aa|
|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP2, PPIase FKBP2, 13 kDa FK506-binding protein, 13 kDa FKBP, FKBP-13, FK506-binding protein 2, FKBP-2, Immunophilin FKBP13, Rotamase, FKBP2, FKBP13|
|Target/Specificity||This FKBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human FKBP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FKBP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein|
|Tissue Location||T-cells and thymus.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds.
Padilla,P.I., Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2322-2327 (2003)
Bush,K.T., Biochem. J. 303 (PT 3), 705-708 (1994)
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