|Application ||WB, IHC-P, FC, E|
|Calculated MW||33743 Da|
|Antigen Region||130-159 aa|
|Other Names||Protein NipSnap homolog 2, NipSnap2, Glioblastoma-amplified sequence, GBAS, NIPSNAP2|
|Target/Specificity||This GBAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human GBAS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GBAS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Widely expressed. Most abundant in heart and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Seroussi, E., et al. Gene 212(1):13-20(1998)
Wang, X.Y., et al. Genomics 49(3):448-451(1998)
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