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BLM Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6782b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
BLM Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
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| Primary Accession | P54132 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 159000 Da |
BLM Antibody (C-term) - Additional info | |
| Gene ID 641 | |
| Other Names BLM; RECQ2; RECQL3; Bloom syndrome protein; DNA helicase, RecQ-like type 2; RecQ protein-like 3 | |
| Target/Specificity This BLM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1316~1346 amino acids from the C-terminal region of human BLM. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BLM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
BLM Antibody (C-term) - Protein Information | |
| Name BLM | |
| Synonyms RECQ2, RECQL3 | |
| Function Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA | |
| Cellular Location Nucleus. | |
BLM Antibody (C-term) - Related products
AP4860b: BLM Antibody (C-term)
AP6782b: BLM Antibody (C-term)
BLM Antibody (C-term) - Application data
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Western blot analysis of BLM Antibody (C-term) (Cat. #AP6782b) in Jurkat cell line lysates (35ug/lane). BLM (arrow) was detected using the purified Pab.
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BLM Antibody (C-term) (Cat. #AP6782b) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BLM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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BLM Antibody (C-term) (Cat. #AP6782b) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
BLM Antibody (C-term) - Research Areas
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BACKGROUND
BLM participates in DNA replication and repair and Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single-and double-stranded DNA in a 3'-5' direction.
REFERENCES
Guey,L.T., et.al., Eur. Urol. (2009) Schuetz,J.M., et.al., BMC Med. Genet. 10, 117 (2009)
