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CRHR2 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CRHR2 Antibody (N-term) AP6787a
    Western blot analysis of CRHR2 Antibody (N-term) (Cat. #AP6787a) in NIH-3T3 cell line lysates (35ug/lane). CRHR2 (arrow) was detected using the purified Pab.
  • IHC-P - CRHR2 Antibody (N-term) AP6787a
    CRHR2 Antibody (N-term) (Cat. #AP6787a) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRHR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - CRHR2 Antibody (N-term) AP6787a
    CRHR2 Antibody (N-term) (Cat. #AP6787a) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13324
Other Accession P47866, Q60748
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47688 Da
Antigen Region 84-114 aa
Additional Information
Gene ID 1395
Other Names Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Target/Specificity This CRHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-114 amino acids from the N-terminal region of human CRHR2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRHR2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRHR2
Synonyms CRF2R, CRH2R
Function G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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CRHR2 is a receptor for corticotropin releasing factor.It Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.


Yerges,L.M.,, J. Bone Miner. Res. (2009)

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$ 295.00
$ 99.00
Cat# AP6787a
(40 western blots)
Availability: In Stock
Bulk Size
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