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CRHR2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • FC - CRHR2 Antibody (Center) AP6787c
    CRHR2 Antibody (Center) (Cat. #AP6787c) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - CRHR2 Antibody (Center) AP6787c
    Western blot analysis of CRHR2 Antibody (Center) (Cat. #AP6787c) in Hela cell line lysates (35ug/lane). CRHR2 (arrow) was detected using the purified Pab.
  • IHC-P - CRHR2 Antibody (Center) AP6787c
    CRHR2 Antibody (Center) (Cat. #AP6787c) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRHR2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • IF - CRHR2 Antibody (Center) AP6787c
    Confocal immunofluorescent analysis of CRHR2 Antibody (Center)(Cat#AP6787c) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13324
Other Accession P47866
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47688 Da
Antigen Region 243-272 aa
Additional Information
Gene ID 1395
Other Names Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Target/Specificity This CRHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the Central region of human CRHR2.
Dilution FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRHR2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRHR2
Synonyms CRF2R, CRH2R
Function G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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CRHR2 is a receptor for corticotropin releasing factor.It Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.


Yerges,L.M.,, J. Bone Miner. Res. (2009)

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$ 295.00
$ 99.00
Cat# AP6787c
(40 western blots)
Availability: In Stock
Bulk Size
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