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FKBP11 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NYL4 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22180 Da |
| Antigen Region | 159-188 aa |
| Gene ID | 51303 |
|---|---|
| Other Names | Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase FKBP11, 19 kDa FK506-binding protein, 19 kDa FKBP, FKBP-19, FK506-binding protein 11, FKBP-11, Rotamase, FKBP11, FKBP19 |
| Target/Specificity | This FKBP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human FKBP11. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FKBP11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FKBP11 |
|---|---|
| Synonyms | FKBP19 |
| Function | PPIases accelerate the folding of proteins during protein synthesis. |
| Cellular Location | Membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.
References
Rulten,S.L., et.al., Mamm. Genome 17 (4), 322-331 (2006)
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