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Calponin-1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | P51911 |
| Other Accession | Q08290, Q08091, Q2HJ38, Q7YRL2 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33170 Da |
| Antigen Region | 10-39 aa |
| Gene ID | 1264 |
|---|---|
| Other Names | Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1 |
| Target/Specificity | This Calponin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human Calponin-1. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Calponin-1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNN1 |
|---|---|
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). |
| Tissue Location | Smooth muscle, and tissues containing significant amounts of smooth muscle |
Provided below are standard protocols that you may find useful for product applications.
Background
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
References
Marsh,W.L., et.al., Appl. Immunohistochem. Mol. Morphol. 17 (3), 216-219 (2009)
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