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Chromogranin-C Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P13521 |
| Other Accession | Q5FZP5 |
| Reactivity | Human |
| Predicted | Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70941 Da |
| Antigen Region | 246-274 aa |
| Gene ID | 7857 |
|---|---|
| Other Names | Secretogranin-2, Chromogranin-C, Secretogranin II, SgII, Secretoneurin, SN, SCG2, CHGC |
| Target/Specificity | This Chromogranin-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the Central region of human Chromogranin-C. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Chromogranin-C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCG2 |
|---|---|
| Synonyms | CHGC |
| Function | Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. |
| Cellular Location | Secreted. Note=Neuroendocrine and endocrine secretory granules |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Chromogranin-C is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
References
Li,L., et.al., Cell Death Differ. 15 (5), 879-888 (2008)
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