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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AADAC Antibody (C-term)   

AADAC Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AADAC Antibody (C-term) AP6805b
    Western blot analysis of AADAC Antibody (C-term) (Cat. #AP6805b) in 293 cell line lysates (35ug/lane). AADAC (arrow) was detected using the purified Pab.
  • IHC-P - AADAC Antibody (C-term) AP6805b
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with AADAC Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - AADAC Antibody (C-term) AP6805b
    Flow cytometric analysis of widr cells using AADAC Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - AADAC Antibody (C-term) AP6805b
    Western blot analysis of AADAC (arrow) using rabbit polyclonal AADAC Antibody (C-term) (Cat. #AP6805b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AADAC gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22760
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45734 Da
Antigen Region 273-300 aa
Additional Information
Gene ID 13
Other Names Arylacetamide deacetylase, AADAC, DAC
Target/Specificity This AADAC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human AADAC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAADAC Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DAC
Function Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein
Tissue Location Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder.
Research Areas
Citations (0)

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Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens.


Saito,S.,, J. Hum. Genet. 48 (5), 249-270 (2003)

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$ 295.00
$ 99.00
Cat# AP6805b
(40 western blots)
Availability: In Stock
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