|Application ||WB, IHC-P, FC, E|
|Calculated MW||28665 Da|
|Antigen Region||50-78 aa|
|Other Names||Collectin-11, Collectin kidney protein 1, CL-K1, COLEC11|
|Target/Specificity||This COLEC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human COLEC11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||COLEC11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N- acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
COLEC11 is a member of the collectin family of C-type lectins, which contain a collagen-like domain and a carbohydrate recognition domain, and play a role in host-defense
Oguri,M., et.al., Am. J. Hypertens. (2009)
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