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RAGE Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q9UQ07 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48014 Da |
| Antigen Region | 206-234 aa |
| Gene ID | 5891 |
|---|---|
| Other Names | MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Renal tumor antigen 1, RAGE-1, MOK, RAGE, RAGE1 |
| Target/Specificity | This RAGE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human RAGE. |
| Dilution | IF~~1:10~50 WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAGE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MOK |
|---|---|
| Synonyms | RAGE, RAGE1 |
| Function | Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9WVS4}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9WVS4}. Nucleus {ECO:0000250|UniProtKB:Q9WVS4} |
| Tissue Location | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
References
Peng,W.H., et.al., Arch. Med. Res. 40 (5), 393-398 (2009)
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