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KCNJ2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNJ2 Antibody (C-term) AP6926c
    Anti-KCNJ2 Antibody (C-term) at 1:1000 dilution + human brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - KCNJ2 Antibody (C-term) AP6926c
    Western blot analysis of KCNJ2 Antibody (C-term) (Cat. #AP6926c) in mouse lung tissue lysates (35ug/lane). KCNJ2 (arrow) was detected using the purified Pab.
  • IHC-P - KCNJ2 Antibody (C-term) AP6926c
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with KCNJ2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - KCNJ2 Antibody (C-term) AP6926c
    KCNJ2 Antibody (C-term) (Cat. #AP6926c) flow cytometry analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63252
Other Accession Q64273, P49656, O18839, P35561, P52186, O19182
Reactivity Human, Mouse
Predicted Bovine, Chicken, Pig, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48288 Da
Antigen Region 401-427 aa
Additional Information
Gene ID 3759
Other Names Inward rectifier potassium channel 2, Cardiac inward rectifier potassium channel, Inward rectifier K(+) channel Kir21, IRK-1, hIRK1, Potassium channel, inwardly rectifying subfamily J member 2, KCNJ2, IRK1
Target/Specificity This KCNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-427 amino acids from the C-terminal region of human KCNJ2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNJ2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ2
Synonyms IRK1
Function Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
Cellular Location Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor
Tissue Location Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain
Research Areas
Citations (0)

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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. This protein is an integral membrane protein and inward-rectifier type potassium channel. This protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is racterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

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$ 295.00
$ 99.00
Cat# AP6926c
(40 western blots)
Availability: In Stock
Bulk Size
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