|Application ||WB, IHC-P, FC, IF, E|
|Other Accession||Q92142, P09810, P17290, P70080|
|Predicted||Chicken, Rabbit, Rat, Xenopus|
|Calculated MW||50985 Da|
|Antigen Region||35-62 aa|
|Other Names||Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH|
|Target/Specificity||This TPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-62 amino acids from the N-terminal region of human TPH1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TPH1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||TPH, TPRH, TRPH|
|Tissue Location||Isoform 2 seems to be less widely expressed than isoform 1|
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Provided below are standard protocols that you may find useful for product applications.
TPH1 is a member of the aromatic amino acid hydroxylase family. This protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter.
Johansson,T.A., et.al., BMC Cancer 9, 321 (2009)
Kuhn,D.M., et.al., J. Neurochem. 68 (5), 2220-2223 (1997)
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