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C9orf156 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BU70 |
| Other Accession | Q4V7E0, Q562D6 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48587 Da |
| Antigen Region | 365-391 aa |
| Gene ID | 51531 |
|---|---|
| Other Names | Nef-associated protein 1, 312-, Thioesterase NAP1, C9orf156, NAP1 |
| Target/Specificity | This C9orf156 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the C-terminal region of human C9orf156. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C9orf156 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRMO {ECO:0000303|PubMed:25063302, ECO:0000312|HGNC:HGNC:30967} |
|---|---|
| Function | S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability (By similarity). |
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Provided below are standard protocols that you may find useful for product applications.
Background
C9orf156 hydrolyzes acyl-CoA thioesters (in vitro). It has a preference for substrates with medium chain length (C10-C14). Inactive towards substrates with C18 or C20 aliphatic chains. Its physiological function is not known.
References
Moreno,L.M., et.al., Hum. Mol. Genet. 18 (24), 4879-4896 (2009)
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