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IGFBP4 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6941c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP6941c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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IGFBP4 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | P22692 |
| Other Accession | NP_001543.2 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 27934 Da |
IGFBP4 Antibody (Center) - Additional info | |
| Gene ID 3487 | |
| Other Names IGFBP4; IBP4; Insulin-like growth factor-binding protein 4 | |
| Target/Specificity This IGFBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human IGFBP4. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions IGFBP4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
IGFBP4 Antibody (Center) - Protein Information | |
| Name IGFBP4 | |
| Synonyms IBP4 | |
| Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors | |
| Cellular Location Secreted. | |
IGFBP4 Antibody (Center) - Related products
AP6941a: IGFBP4 Antibody (N-term)
AP6941c: IGFBP4 Antibody (Center)
RI12663: IGFBP4 predesign siRNA
BP6941a: IGFBP4 Antibody (N-term) Blocking Peptide
IGFBP4 Antibody (Center) - Application data
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IGFBP4 Antibody (Center) (Cat. #AP6941c) western blot analysis in mouse lung tissue lysates (15ug/lane).This demonstrates the IGFBP4 antibody detected IGFBP4 protein (arrow).
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IGFBP4 antibody (Center) (Cat. #AP6941c) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGFBP4 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
IGFBP4 Antibody (Center) - Research Areas
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BACKGROUND
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
REFERENCES
Giroux, S., et al. Bone 47(5):975-981(2010) Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010) Bartling, B., et al. Int. J. Mol. Med. 25(1):89-96(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) : Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
