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BACH Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP6949b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP6949b-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
BACH Antibody (C-term) - Product info | |
| Application | WB, FC, IHC
|
| Primary Accession | O00154 |
| Other Accession | Q64559, Q91V12 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 41796 Da |
BACH Antibody (C-term) - Additional info | |
| Gene ID 11332 | |
| Other Names ACOT7; BACH; Cytosolic acyl coenzyme A thioester hydrolase; Acyl-CoA thioesterase 7; Brain acyl-CoA hydrolase; CTE-IIa; Long chain acyl-CoA thioester hydrolase | |
| Target/Specificity This BACH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human BACH. | |
| Dilution WB~~1:100~500WB~~1:1000 FC~~1:10~50 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BACH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
BACH Antibody (C-term) - Protein Information | |
| Name ACOT7 | |
| Synonyms BACH | |
| Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl- CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA | |
| Cellular Location Isoform 4: Cytoplasm. Isoform 1: Mitochondrion. | |
| Tissue Location Isoform 4 is expressed exclusively in brain. | |
BACH Antibody (C-term) - Related products
AP6949b: BACH Antibody (C-term)
AP6949c: BACH Antibody (Center)
RI10067: ACOT7 predesign siRNA
DC04511: Human ACOT7 cDNA Clone
BACH Antibody (C-term) - Application data
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Western blot analysis of BACH Antibody (C-term) (Cat. #AP6949b) in mouse brain tissue lysates (35ug/lane).BACH (arrow) was detected using the purified Pab.
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BACH Antibody (C-term) (Cat. #AP6949b) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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BACH Antibody (C-term) (Cat. #AP6949b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BACH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
BACH Antibody (C-term) - Research Areas
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BACKGROUND
BACH is a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy.
REFERENCES
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Yoshida, T., et al. Int. J. Mol. Med. 24(4):539-547(2009)
