- CITATIONS: 0
|Application ||WB, IHC-P, FC, E|
|Calculated MW||112916 Da|
|Antigen Region||986-1014 aa|
|Other Names||Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21, CR2, C3DR|
|Target/Specificity||This CR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 986-1014 amino acids from the C-terminal region of human CR2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen|
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Provided below are standard protocols that you may find useful for product applications.
CR2 is a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes.
Rikova,K., et.al., Cell 131 (6), 1190-1203 (2007)
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