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MSRB2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q9Y3D2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19536 Da |
| Antigen Region | 44-73 aa |
| Gene ID | 22921 |
|---|---|
| Other Names | Methionine-R-sulfoxide reductase B2, mitochondrial, MsrB2, 184-, MSRB2, CBS-1, MSRB |
| Target/Specificity | This MSRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the Central region of human MSRB2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MSRB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MSRB2 |
|---|---|
| Synonyms | CBS-1, MSRB |
| Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. |
| Cellular Location | Mitochondrion |
| Tissue Location | Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
MSRB2 catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.
References
Cabreiro,F., et.al., J. Biol. Chem. 283 (24), 16673-16681 (2008)
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$ 182.50
$ 70.00
Cat# AP6980c
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