|Application ||IHC-P, E|
|Calculated MW||57449 Da|
|Antigen Region||103-132 aa|
|Other Names||Lymphocyte activation gene 3 protein, LAG-3, Protein FDC, CD223, LAG3, FDC|
|Target/Specificity||This LAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human LAG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LAG3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in lymphocyte activation. Binds to HLA class-II antigens.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||On cell surface of activated NK and T- lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains.
Smyth,D.J., et.al., BMC Med. Genet. 7, 20 (2006)
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