|Application ||WB, E|
|Other Accession||Q4FZZ1, Q8BX57, Q7Z7A4|
|Calculated MW||43849 Da|
|Antigen Region||221-251 aa|
|Other Names||PX domain-containing protein kinase-like protein; Modulator of Na;K-ATPase; MONaKA; PXK;|
|Target/Specificity||This PXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-251 amino acids from the Central region of human PXK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PXK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
PXK is widely expressed in all tissues examined except in heart. It binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. However, the protein kinase domain is predicted to be catalytically inactive.
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
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