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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Ketohexokinase (KHK) Antibody (N-term)   

Ketohexokinase (KHK) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Ketohexokinase (KHK) Antibody (N-term) AP7069a
    Western blot analysis of KHK (arrow) using rabbit polyclonal Ketohexokinase (KHK) Antibody (N-term) (Cat. #AP7069a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the KHK gene (Lane 2) (Origene Technologies).
  • WB - Ketohexokinase (KHK) Antibody (N-term) AP7069a
    The anti-KHK Pab (Cat. #AP7069a) is used in Western blot to detect KHK in mouse liver tissue lysate (Lane 1) and 293 cell lysate (Lane 2).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50053
Other Accession Q02974, P97328
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32523 Da
Antigen Region 18-46 aa
Additional Information
Gene ID 3795
Other Names Ketohexokinase, Hepatic fructokinase, KHK
Target/Specificity This Ketohexokinase (KHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human Ketohexokinase (KHK).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKetohexokinase (KHK) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KHK (HGNC:6315)
Function Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Tissue Location Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
Research Areas
Citations (0)

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Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Hayward, B.E., et al., Eur. J. Biochem. 257(1):85-91 (1998).
Bonthron, D.T., et al., Hum. Mol. Genet. 3(9):1627-1631 (1994).

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$ 295.00
$ 99.00
Cat# AP7069a
(40 western blots)
Availability: In Stock
Bulk Size
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